The MSU BI team has extensive experience working with a wide variety of clients from different fields and in performing chemical processes on a commercial scale.
The Holland scale-up and production facility provides specialty chemical process development, proof of concept and manufacturing resources allowing organizations to quickly and cost effectively extend their capabilities without committing the capital to build a facility.
The scale-up facility has 31,400 liters of glass-lined, Hastelloy and stainless steel capacity. The facility is rated as Class I, Division I, Group D and is Process Safety Management (PSM) compliant, has a flexible State of Michigan Air Permit and employs personnel that are qualified to handle hazardous waste. Our team has experience performing reactions from -100°C to 230°C and from full vacuum to 50psi.
Equipment
Stills
Equipped with temperature-controlled graphite condensers.
Operating Parameters
- Temperature: -20 to 130°C
- Pressure: Full Vacuum to 50 psig
- Variable Agitation
Vessel Sizes
- 2 x 4000 L Glass Lined
- 2 x 2000 L Glass-Lined
- 2 x 800 L Stainless Steel
- 800 L Hastelloy C276
- 400 L Glass-Lined
- 200 L Glass-Lined
Reactors
Operating Parameters
- Temperature: -20 to 130°C
- Pressure: Full Vacuum to 50 psig
- Variable Agitation
Vessel Sizes
- 4000 L Glass Lined
- 2 x 2000 L Glass-Lined
- 800 L Glass-Lined
- 400 L Glass-Lined
- 200 L Glass-Lined
- 120 L Glass-Lined
- 80 L Glass-Lined
Tanks
Operating Parameters
- Pressure: Full Vacuum to 50 psig
Vessel Sizes
- 2000 L Glass-Lined
- 4000 L Glass Lined
- 800 L Glass-Lined
Dryers
Operating Parameters
- Temperature Range: 20 to 95°C
- Pressure Range: Atmospheric to Full Vacuum
Vessel Sizes
- 4 x Epoxy Lined Vacuum Tray Dryers (~250 kg capacity/each)
- 400 L Glass-Lined Rotary Vacuum Dryer (~150 kg
capacity) - 850 L Geudu Pan Dryer, Hastelloy C22
Filters
- Niagara Filters, 316 Stainless Steel
- 18 in – 4 plate
- 18 in – 16 plate
- 2 x 40 in Basket Centrifuge, Hastelloy C276
- Bag Filter
- Cartridge Filters
Filter Dryers
Operating Parameters
- Temperature Range: 20 to 95°C
- Pressure Range: Full Vacuum to 50 psig
- Variable Agitation
Vessel Sizes
- 400 L Cogeim, Hastelloy C276
- 2,000 L Rosenmund, 316 Stainless Steel
Specialized Equipment
- 400 L Low Temperature Hastelloy C276 Reactor
- Cooling capability with Liquid Nitrogen to -100°C at 5 psig; or
- Operating Temperature range: 20 to 95°C at 50 psig
- 400 L Hastelloy C276 Reactor
- Operating Temperature range 20 to 95°C at 50 psig
- 120 L Glass-Lined High Temperature Still with 316 Fractionation Column or 316 Stainless Steel Riser
- Heating capability to 230 °C
- 150 sq. ft. Cold Room
Analytical Capabilities
- GC - Gas Chromatography
- GC/MS - Gas Chromatography-Mass Spectrometry
- HPLC - High-Performance Liquid Chromatography
- DSC - Differential Scanning Calorimetry
- KF - Karl Fisher Titration
- LOD - Loss on Drying
- NMR - Nuclear Magnetic Resonance
Lab Space
The institute in Holland offersextensive laboratory space rental. The site is also home to embedded researchers from private and public sector collaborator organizations. These opportunities help support MSU’s efforts to promote the economic development of Michigan and the nation.